Your doctor may have you take an H2 blocker twice daily for up to 6 weeks or a proton pump inhibitor (PPI), which we will cover next. If your reflux is more frequent (2 or more times per week) or severe, you may have GERD, which is a more severe form of reflux. It’s very important to know that almost all H2 blockers don’t work well after a period of time since the stomach adjusts and they become much less effective. Once your acid reflux improves, stop the medication. Do not take the maximum daily dose continuously for more than 2 weeks, unless directed by your doctor. But remember: H2 blockers are only good for short-term use. If symptoms persist, you can take one more dose within 24 hours. To prevent reflux symptoms, both famotidine and cimetidine work better when taken 10 to 60 minutes before eating food or drinking beverages that cause reflux. But to date, FDA’s testing has not found this substance in famotidine or cimetidine products. Ranitidine (Zantac), another H2 blocker, was recently removed from the market because it was found to contain higher-than-acceptable levels of cancer-causing substances.
If you have mild reflux symptoms that occur less than two times a week, you can start with a low dose of famotidine (Pepcid) or cimetidine (Tagamet). They block histamine, one of the body’s inflammatory agents, from stimulating the stomach to produce acid. H2 blockers are short-term preventative medications that decrease stomach acid.